Single-cell variability in multicellular organisms
نویسندگان
چکیده
منابع مشابه
Bacteria as Multicellular Organisms
W ithout bacteria, life on earth could not exist in its present form. Bacteria are key play ers in many geochemical processes, including the fundamental nitrogen, carbon and sulfur cycles, which are critical to the circulation of life's basic elements. If these processes were to grind to a halt, the planet's soils, wa ters and atmosphere would become inhospitable for life. Yet in spite of suc...
متن کاملSelection for synchronized cell division in simple multicellular organisms
The evolution of multicellularity was a major transition in the history of life on earth. Conditions under which multicellularity is favored have been studied theoretically and experimentally. But since the construction of a multicellular organism requires multiple rounds of cell division, a natural question is whether these cell divisions should be synchronous or not. We study a simple populat...
متن کاملThe origins of multicellular organisms.
Multicellularity has evolved in several eukaryotic lineages leading to plants, fungi, and animals. Theoretically, in each case, this involved (1) cell-to-cell adhesion with an alignment-of-fitness among cells, (2) cell-to-cell communication, cooperation, and specialization with an export-of-fitness to a multicellular organism, and (3) in some cases, a transition from "simple" to "complex" multi...
متن کاملOrigin of complexity in multicellular organisms.
Through extensive studies of dynamical system modeling cellular growth and reproduction, we find evidence that complexity arises in multicellular organisms naturally through evolution. Without any elaborate control mechanism, these systems can exhibit complex pattern formation with spontaneous cell differentiation. Such systems employ a "cooperative" use of resources and maintain a larger growt...
متن کاملInfection and cancer in multicellular organisms.
Evolutionary considerations suggest that oncogenic infections should be pervasive among animal species. Infection-associated cancers are well documented in humans and domestic animals, less commonly reported in undomesticated captive animals, and rarely documented in nature. In this paper, we review the literature associating infectious agents with cancer to evaluate the reasons for this patter...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Communications
سال: 2018
ISSN: 2041-1723
DOI: 10.1038/s41467-017-02710-x